Penter Lab Cancer and immune cell co-evolution at Charité - Universitätsmedizin Berlin

Paper on origins of CLL published!

The origins of MBL and CLL remain elusive. Using mitochondrial genetics and epigenetic/transcriptional profiling at the single cell level, we trace these roots in a cohort of 24 individuals. Finally published in Genome Biology.

Publisher Correction: Single-cell epigenetic and transcriptomic states across the continuum of monoclonal B cell lymphocytosis to chronic lymphocytic leukemia
Publisher Correction: Single-cell epigenetic and transcriptomic states across the continuum of monoclonal B cell lymphocytosis to chronic lymphocytic leukemia
Anja C. Rathgeber, Stacey M. Fernandes, Adi Nagler, Shuqiang Li, David M. Dorfman, ..., Jennifer R. Brown, Kenneth J. Livak, Leif S. Ludwig, Catherine J. Wu, Livius Penter
Genome Biology   ·   02 Jun 2026   ·   doi:10.1186/s13059-026-04135-6
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